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Renal and vascular physiology and phisiopathology

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  • Campillo S, Gutiérrez-Calabrés E, García-Miranda S, Griera M, Fernández Rodríguez L, de Frutos S, Rodríguez-Puyol D, Calleros L.

    Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease.

    CELL COMMUNICATION AND SIGNALING . 22(1): 264-264.

    [doi:10.1186/s12964-024-01646-2]

  • Martín-Vírgala J, Martín-Carro B, Fernández-Villabrille S, Ruiz-Torres MP, Gómez-Alonso C, Rodríguez-García M, Fernández-Martín JL, Alonso-Montes C, Panizo S, Cannata-Andía JB, Naves-Díaz M, Carrillo-López N.

    Soluble Klotho, a Potential Biomarker of Chronic Kidney Disease-Mineral Bone Disorders Involved in Healthy Ageing: Lights and Shadows.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES . 25(3): . Number of citations: 4

    [doi:10.3390/ijms25031843]

  • de Frutos S, Griera M, Lavín-López MDP, Martínez-Rovira M, Martínez-Rovira JA, Rodríguez-Puyol M, Rodríguez-Puyol D.

    A new graphene-based nanomaterial increases lipolysis and reduces body weight gain through integrin linked kinase (ILK)

    BIOMATERIALS SCIENCE . 11(14): 4916-4929.

    [doi:10.1039/d2bm01791a]

  • Martínez-Arias L, Fernández-Villabrille S, Alonso-Montes C, García-Navazo G, Ruíz-Torres MP, Alajarín R, Alvarez-Builla J, Gutiérrez-Calabres E, Vaquero-López JJ, Carrillo-López N, Rodríguez-Puyol D, Cannata-Andía JB, Panizo S, Naves-Díaz M.

    Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure.

    Nutrients . 15(8): .

    [doi:10.3390/nu15081820]

  • Alcalde-Estévez E, Sosa P, Asenjo-Bueno A, Plaza P, Valenzuela PL, Naves-Díaz M, Olmos G, López-Ongil S, Ruiz-Torres MP.

    Dietary phosphate restriction prevents the appearance of sarcopenia signs in old mice.

    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE . 14(2): 1060-1074.

    [doi:10.1002/jcsm.13194]

  • Martín-Vírgala J, Fernández-Villabrille S, Martín-Carro B, Tamargo-Gómez I, Navarro-González JF, Mora-Fernández C, Calleros L, Astudillo-Cortés E, Avello-Llano N, Mariño G, Dusso AS, Alonso-Montes C, Panizo S, Cannata-Andía JB, Naves-Díaz M, Carrillo-López N.

    Serum and Urinary Soluble a-Klotho as Markers of Kidney and Vascular Impairment.

    Nutrients . 15(6): .

    [doi:10.3390/nu15061470]

  • García-Marín J, Rodríguez-Puyol D, Vaquero JJ.

    Insight into the mechanism of molecular recognition between human Integrin-Linked Kinase and Cpd22 and its implication at atomic level

    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN . 36(8): 575-589. Number of citations: 2

    [doi:10.1007/s10822-022-00466-1]

  • Campillo S, Bohorquez L, Gutiérrez-Calabrés E, García-Ayuso D, Miguel V, Griera M, Calle Y, de Frutos S, Rodríguez-Puyol M, Rodríguez-Puyol D, Calleros L.

    Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation.

    EXPERIMENTAL AND MOLECULAR MEDICINE . 54(3): 226-238. Number of citations: 1

    [doi:10.1038/s12276-022-00738-8]

  • de Frutos S, Griera M, Hatem-Vaquero M, Campillo S, Gutiérrez-Calabres E, García-Ayuso D, Pardo M, Calleros L, Rodríguez-Puyol M, Rodríguez-Puyol D.

    The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo.

    CELL BIOSCI . 12(1): 10-10.

    [doi:10.1186/s13578-022-00746-1]

  • Mendoza-Pitti, Luis, Manuel Gomez-Pulido, Jose, Vargas-Lombardo, Miguel, Gomez-Pulido, Juan A., Polo-Luque, Maria-Luz, Rodriguez-Puyol, Diego.

    Machine-Learning Model to Predict the Intradialytic Hypotension Based on Clinical-Analytical Data

    IEEE Access . 10: 72065-72079.

    [doi:10.1109/ACCESS.2022.3189018]

  • Garcés-Jiménez A, Calderón-Gómez H, Gómez-Pulido JM, Gómez-Pulido JA, Vargas-Lombardo M, Castillo-Sequera JL, Aguirre MP, Sanz-Moreno J, Polo-Luque ML, Rodríguez-Puyol D.

    Medical Prognosis of Infectious Diseases in Nursing Homes by Applying Machine Learning on Clinical Data Collected in Cloud Microservices

    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH . 18(24): . Number of citations: 2

    [doi:10.3390/ijerph182413278]

  • Garcia-Marin J, Griera-Merino M, Matamoros-Recio A, de Frutos S, Rodríguez-Puyol M, Alajarín R, Vaquero JJ, Rodríguez-Puyol D.

    Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with alpha-Parvin

    ACS MEDICINAL CHEMISTRY LETTERS . 12(11): 1656-1662. Number of citations: 4

    [doi:10.1021/acsmedchemlett.1c00183]

  • Sosa P, Alcalde-Estévez E, Asenjo-Bueno A, Plaza P, Carrillo-López N, Olmos G, López-Ongil S, Ruiz-Torres MP.

    Aging-related hyperphosphatemia impairs myogenic differentiation and enhances fibrosis in skeletal muscle

    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE . 12(5): 1266-1279. Number of citations: 2

    [doi:10.1002/jcsm.12750]

  • Garcia-Marin, J, Griera, M, Alajarin, R, Rodriguez-Puyol, M, Rodriguez-Puyol, D, Vaquero, JJ.

    A Computer-Driven Scaffold-Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2-a]quinoxaline Core

    Chemmedchem . 16(18): 2895-2906. Number of citations: 4

    [doi:10.1002/cmdc.202100338]

  • Bouarich, Hanane, Chavez Guillen, Alina, Rodriguez Puyol, Diego.

    Kidney and hypertension in older adults

    MEDICINA CLINICA . 157(4): 178-184.

    [doi:10.1016/j.medcli.2021.02.008]

  • Sánchez-Alonso P, Griera M, García-Marín J, Rodríguez-Puyol M, Alajarín R, Vaquero JJ, Rodríguez-Puyol D.

    Pyrrolo[1,2-a]quinoxal-5-inium salts and 4,5-dihydropyrrolo[1,2-a] quinoxalines: Synthesis, activity and computational docking for protein tyrosine phosphatase 1B

    BIOORGANIC & MEDICINAL CHEMISTRY . 44: 116295-116295. Number of citations: 2

    [doi:10.1016/j.bmc.2021.116295]

  • Asenjo-Bueno A, Alcalde-Estévez E, El Assar M, Olmos G, Plaza P, Sosa P, Martínez-Miguel P, Ruiz-Torres MP, López-Ongil S.

    Hyperphosphatemia-Induced Oxidant/Antioxidant Imbalance Impairs Vascular Relaxation and Induces Inflammation and Fibrosis in Old Mice

    ANTIOXIDANTS . 10(8): . Number of citations: 4

    [doi:10.3390/antiox10081308]

  • de Abajo FJ, Rodríguez-Miguel A, Rodríguez-Martín S, Lerma V, García-Lledó A.

    Impact of in-hospital discontinuation with angiotensin receptor blockers or converting enzyme inhibitors on mortality of COVID-19 patients: a retrospective cohort study

    BMC MEDICINE . 19(1): 118-118. Number of citations: 10

    [doi:10.1186/s12916-021-01992-9]