Diabetes, Obesity and Human Reproduction

2023 Activity indicators

  • 3 competitive national public projects: ISCIII
  • 6 clinical studies led
  • 1 competitive HR contract
  • 16 publications
  • IF: 82.60
  • Q1 publications: 8 (50%)
  • D1 publications: 7 (44%)
  • 2 thesis
  • Evaluators of public agencies: 4 PI
  • Members of editorial committees: 2 PI
  • A European patent application EP19382836.5 entitled "Combined therapy comprising an inhibitor of interleukin-17 activity and a vitamin D receptor agonist", with PCT/ EP2020/077227 and European national phase EP20785714.5
  • 1 document with recommendations (PMID: 37359897)
  • 1 action with impact on society: Madrid Science Week

Milestones

  1. Dr. Nattero was awarded the projects "Impact of the menstrual cycle on the control of type 1 diabetes mellitus in women of childbearing age with an advanced closed-loop system" funded by the Ministry of Science, Innovation and Universities and "Non-alcoholic fatty liver disease in people with type 1 diabetes in Spain" funded by CIBERDEM. 
  2. Participation of Dr. Escobar in the drafting of the "Recommendations for the measurement of sexual steroids in clinical practice". The position paper reviews the current state of the standardization of estradiol and testosterone measurement methods and their impact on different clinical situations (Adv Lab Med. PMID: 37359897)
  3. Millán N, Luque M. Nattero l, Escobar HF. PCOS during the menopausal transition and after menopause: a systematic review and meta-analysis. Hum Reprod Update. 2023;29(6):741-772. DOI: 10.1093/humupd/dmad015. PMID: 37353908. This work confirms that the clinical and biochemical characteristics of women with polycystic ovary syndrome (PCOS) persist during and after menopause, showing significant cardiometabolic associations.
  4. Escobar HF, Martínez MÁ, Insenser M, Cañellas N, Correig X, Luque M. Serum metabolomics profiling by proton nuclear magnetic resonance spectroscopy reveals sexual dimorphism and masculinization of intermediate metabolism in women with polycystic ovary syndrome (PCOS). Biol Sex Differ. 2023;14(1): 21 - 21. DOI:10.1186/s13293-023-00507-w. PMID: 37076926. This work analyzes the differences in the metabolomic profile between women with and without polycystic ovary syndrome and men. The results showed sexual dimorphism and masculinization of intermediary metabolism in women with PCOS.
  5. A PFIS contract has been awarded, under the direction of Dr. Nattero, to develop the Doctoral Thesis entitled: "Sexual dimorphism and inflammatory biomarkers in patients with type 1 diabetes mellitus and cardiac autonomic neuropathy."

Bibliometrics

  Articles Accum. IF Mean IF Articles Q1 or Q2 % in Q1 or Q2 Articles D1 % in D1
2019 15 61.25 4.08 12 80 3 20
2020 10 44.07 4.41 9 90 1 10
2021 16 128.57 8.08 13 81 3 19
2022 13 67.69 5.21 7 53,85 1 8
2023 16 82.60 6.35 9 56 7 44
  70 384.18 5.62 50 72 15 20

*Only original articles, editorials, guidelines and reviews

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