Milestones

1. Development of a new animal model for therapeutic testing of antioxidant and neuroprotective agents (Espitia-Arias MD, de la Villa P, Paleo-García V, Germain F, Milla-Navarro S. Oxidative Model of Retinal Neurodegeneration Induced by Sodium Iodate: Morphofunctional Assessment of the Visual Pathway. Antioxidants (Basel). 2023 Aug 10;12(8):1594. DOI: 10.3390/antiox12081594. PMID: 37627589)
2. Demonstration of the functional origin of electroretinogram oscillatory potentials (Liao F, Liu H, Milla-Navarro S, Villa P, Germain F. Origin of Retinal Oscillatory Potentials in the Mouse, a Tool to Specifically Locate Retinal Damage. Int J Mol Sci. 2023 Feb 4;24(4):3126. DOI: 10.3390/ijms24043126. PMID: 36834538)
3. Demonstration of the importance of calcium sensors in the regulation of neuronal survival processes (Muñoz-Reyes D, McClelland LJ, Arroyo-Urea S, Sánchez-Yepes S, Sabín J, Pérez-Suárez S, Menendez M, Mansilla A, García-Nafría J, Sprang S, Sanchez-Barrena MJ. The neuronal calcium sensor NCS-1 regulates the phosphorylation state and activity of the Gα chaperone and GEF Ric-8A. Elife. 2023 Nov 29:12:e86151. DOI: 10.7554/eLife.86151. PMID: 38018500)
4. Description of new elements required for the formation of highly specialized synapses (Jimeno D, Lillo C, de la Villa P, Calzada N, Santos E, Fernández-Medarde A. GRF2 Is Crucial for Cone Photoreceptor Viability and Ribbon Synapse Formation in the Mouse Retina. Cells. 2023 Nov 4;12(21):2574. DOI: 10.3390/cells12212574. PMID: 37947653)
5. Consolidation of the group with the incorporation of members with expertise in basic biochemistry and pharmacology techniques.