Biological chemistry

Group leader

Manuel Ángel Fernández Rodríguez

mangel.fernandezr(ELIMINAR)@uah.es

Principal Investigator

  • David Sucunza Sáenz
  • Estibaliz Merino Marcos
  • Javier Carreras Pérez-Aradros
  • Patricia García García
  • José Luis Aceña Bonilla

Collaborating Staff

  • Ana María Cuadro Palacios
  • Alberto Domingo Galán
  • Álvaro González Molina
  • Clara Mañas Hernández
  • Guillermo Germán Otárola Tejada
  • Javier García Marín
  • Marta Durán Martínez
  • Jaime Mateos Gil
  • Rafael Martín Romero Segura
  • Mercedes Zurro de la Fuente
  • Ana Maria Carozo Fernandez
Imagen equipo

Group leader

Manuel Ángel Fernández Rodríguez

mangel.fernandezr(ELIMINAR)@uah.es

Principal Investigator

  • David Sucunza Sáenz
  • Estibaliz Merino Marcos
  • Javier Carreras Pérez-Aradros
  • Patricia García García
  • José Luis Aceña Bonilla

Collaborating Staff

  • Ana María Cuadro Palacios
  • Alberto Domingo Galán
  • Álvaro González Molina
  • Clara Mañas Hernández
  • Guillermo Germán Otárola Tejada
  • Javier García Marín
  • Marta Durán Martínez
  • Jaime Mateos Gil
  • Rafael Martín Romero Segura
  • Mercedes Zurro de la Fuente
  • Ana Maria Carozo Fernandez

Strategic objectives

The group's research activity is aimed at the design, synthesis and evaluation of small molecules of biological interest or pharmacological activity. For this aim, we collaborate with groups that are experts in validated and emerging targets in different therapeutic areas. The active lines of research focus on the development of new inhibitors of several targets, the search for reagents for cell staining and bioimaging and the development of synthetic methodology applicable to carbo- and heterocycles of biological interest and PET reagents.

Research lines

  • Medicinal chemistry strategies in kidney disease.
  • Estrategias de Química Médica en la enfermedad renal.
    • Development of new inhibitors on targets involved in kidney disease (calpains, PTP1B and NIK).
    • Vehiculation of PNAs and drugs to the renal environment.
    • Search for alternatives to the use of glucose in peritoneal dialysis solutions.
  • Design and study of new chromophores for multiphoton absorption with potential application in cellular staining and bioimaging.
  • Development of synthetic methodology for carbo- and heterocycles of biological interest. Organocatalysis. Photocatalysis
  • Synthesis, reactivity and applications of BN-arenes.

Location

Dpt. Organic and Inorganic Chemistry


Pharmacy Faculty
Alcala University
0034 91 885 4761

Link to UAH group

Keywords

cell staining and bioimaging, chronic renal disease, bioactive azaheterocycles and azaborines, metal catalysis, PET reagents, peptides