Strategic objectives

Design, synthesis, and evaluation of small molecules of biological interest or pharmacological activity. To this end, it maintains collaborations with expert groups on validated and emerging targets in different therapeutic areas. Active research lines focus on the development of new inhibitors against various targets involved in kidney disease, the search for reagents for cell staining and bioimaging, and the development of synthetic methodologies applicable to carbo- and heterocycles of biological interest.

Research lines

• Medicinal chemistry strategies in kidney disease:
  • Development of novel inhibitors targeting pathways involved in kidney disease (calpains, PTP1B, and NIK).
  • Delivery of PNAs and drugs to the renal environment.
  • Search for alternatives to glucose in peritoneal dialysis solutions.
• Design and study of novel chromophores for multiphoton absorption with potential applications in cell staining and bioimaging.
• Development of synthetic methodologies for carbo- and heterocycles of biological interest. Organocatalysis. Photocatalysis.
• Synthesis, reactivity, and applications of BN-arenes.