Renal and vascular physiology and phisiopathology
Group leader
Diego María Rodríguez Puyol
Principal Investigator
- María Piedad Ruiz Torres
 - Laura Calleros Basilio
 - José Manuel Gómez Pulido
 
Collaborating Staff
- Gema Olmos Centenera
 - Sergio de Frutos García
 - Jose Luis Castillo Sequera
 - María Luz Polo Luque
 - Ariadna Moreno Piedra
 - Francisco Javier Bueno Guillén
 - Alberto Garcés Jiménez
 - Juan Antonio Gómez Pulido
 - Sergio García Villoria
 - Alba Silvestre Vargas
 - Elena Alcalde Estévez
 - Belen Molina Martinez
 
            Group leader
Diego María Rodríguez Puyol
Principal Investigator
- María Piedad Ruiz Torres
 - Laura Calleros Basilio
 - José Manuel Gómez Pulido
 
Collaborating Staff
- Gema Olmos Centenera
 - Sergio de Frutos García
 - Jose Luis Castillo Sequera
 - María Luz Polo Luque
 - Ariadna Moreno Piedra
 - Francisco Javier Bueno Guillén
 - Alberto Garcés Jiménez
 - Juan Antonio Gómez Pulido
 - Sergio García Villoria
 - Alba Silvestre Vargas
 - Elena Alcalde Estévez
 - Belen Molina Martinez
 
Strategic objectives
- Four active research projects from the National Plan.
 - Six publications in the first quartile of their area of expertise.
 - Two demonstrably active collaborations with other members of IRYCIS or the Ramón y Cajal University Hospital (supported by joint projects, publications, and/or lines of development).
 - At least one annual scientific talk for the entire Institute (by invitation).
 - Facilitate the collaboration of other IRYCIS members in at least one annual teaching activity at the University of Alcalá.
 - Regular collaboration with at least one private company.
 
Research lines
- Integrin-linked kinase: a potential biomarker of chronic kidney disease (CKD) progression and a modulator of monocyte dysfunction responsible for cardiovascular damage.
 - Integrin-linked kinase: a role in the progression of insulin resistance and the development of obesity.
 - Importance of phosphorus in the genesis of vascular disorders in the elderly and patients with arteriosclerosis. New approaches to assessing the problem.
 - Importance of phosphorus in the genesis of sarcopenia in the elderly and patients with chronic kidney disease. New approaches to assessing the problem.
 - Massive data analysis in the prevention of complications associated with hemodialysis.
 
Location
Faculty of Medicine
Alcalá University
+34 91 887 81 00 (ext. 2562)
Keywords
chronic kidney disease, extracellular matrix, integrin-linked kinase, GLUT4, AQP2, endothelial dysfunction, phosphorus, sarcopenia, cellular senescence, hemodialysis